Methylfolate

Feefo Product Rating 4.7 out of 5 with 103 reviews
£13.90 from

Our small, easy to take wholefood capsules provide folic acid as methylfolate (5-MTHF) for optimum absorption.

This is the most stable and naturally active form of folate ready for use by your body.

Folic acid has to undergo a number of steps within the body in order to be converted to the active form however our supplements are already in the active methylated form. 

Best used as a top up product on the advice of a health practitioner: if you have been advised to supplement with methylfolate, we would firstly recommend taking an all-round multivitamin which includes all the B vitamins, including B12.

If you are unsure and would like further information, please complete our FREE health questionnaire, or email our nutritional therapists on nutrition@cytoplan.co.uk 

Product Code
3319/SB3319
  • Provides folic acid as methylfolate (5-MTHF) for optimum absorption

  • Methylfolate is 7 x more bioeffective than folic acid and the safest form of folate 

  • Small easy to take capsules

  • Recommended folate (folic acid) level for pregnancy and preconception 

     

About our Methylfolate supplement 

Provides folic acid as methylfolate, 400ug per capsule. In a wholefood, stable and active form that is better used by your body than folic acid. Fulfils all the known uses of folic acid. 

Folate supplement benefits vs folic acid 

Many supplements contain folic acid; however folic acid must undergo several steps within the body to be converted to the active form – 5-MTHF. The final step in this conversion is carried out in your body by an enzyme called MTHFR and some people have genetic mutations which means this enzyme has reduced efficiency in converting folic acid to 5MTHF. 

Methylfolate does not need to be converted; it is in the active form, ready for use by the body. 

Functions of folic acid

Folic acid contributes to normal homocysteine metabolism. This is important as high homocysteine is a risk factor for several chronic diseases, including cardiovascular disease and cognitive decline.

Folate is used in the methylation cycle, something which occurs in all the cells of your body. Methylation is a chemical process that occurs a billions of times a second and is needed for the proper functioning of almost all body systems.  

Methylation functions: 

  • Detoxing environmental toxins 
  • Regulating hormones 
  • Energy production 
  • Production of neurotransmitters 
  • Production of immune cells 
  • Metabolism of homocysteine 
  • and many more! 

Methylation involves transferring molecules called ‘methyl groups’ to and from compounds to allow them to work optimally in the body. Methyl donors include folate, B12 and B6, among other nutrients, which are vital to normal methylation and therefore homocysteine metabolism.

Methyl folate (or 5-MTHF) is readily able to donate a methyl group to the amino acid homocysteine which is then converted to methionine, which is then used to form S-adenosylmethionine (SAM-e). SAM-e is used in many metabolic processes that require a methyl group. 

Folate contributes to normal: 

  • psychological function. 
  • blood formation. 
  • homocysteine metabolism. 
  • maternal tissue growth during pregnancy. 
  • immune system function. 
  • amino acid synthesis – can we give an example? 
  • contributes to the reduction of tiredness and fatigue. 
  • has a role in the process of cell division. 

What is the best folic acid for pregnancy? 

Supplementing with folic acid during preconception and pregnancy increases the mother’s folate status. Low levels in mum are a risk factor in the development of neural tube defects, such as spina bifida, in the developing foetus. 

You can find the government recommended daily dose of 400µg of folic acid in its optimally absorbed and naturally active form of methylfolate in our comprehensive pregnancy multivitamin and mineral, Pregna-Plan

Methylfolate - 1 capsule will provide on average:
Active Nutrient Strength %NRV*
Folic Acid as 5 methyltetrahydrofolate 400µg 200
+NRV = Nutritional Reference Value
* Indicates no NRV
Ingredients:

Folic acid (as 5 methyltetrahydrofolate), alfalfa (Medicago sativa) powder, brown rice flour, natural rice extract, Hydroxypropyl methylcellulose (capsule shell).

Suggested Intake:

One capsule daily with food as a food supplement or as directed by a practitioner.

Suitable for:

Vegetarians, vegans and for people with Candida and yeast sensitivities.

Contraindications:

None.

Non-Active Ingredients:

Maltodextrin, stearic acid, HPMC (vegetable cellulose, capsule shell).

Non GM & Free From:

GMO, wheat, gluten, soy, dairy, added sugar, colourings & flavourings.

Storage:

Keep cool, dry & out of direct sunlight.

For UK-delivered orders that are under £25.00, we charge a nominal postage and packing fee of £4.50. UK orders of £25.00 and over are DELIVERED FREE OF CHARGE. 

Dependent on weight, your order will either be sent by Royal Mail tracked service or via our nominated courier. A signature is required on receipt of the goods if delivered by our courier. 

Please check all requirements (import taxes, customs regulations etc) regarding deliveries to countries outside the UK. Cytoplan Ltd cannot be held responsible for parcels that do not comply with the import regulations of the destination country.

We cannot guarantee next day delivery, although you should receive your order within 2-3 working days. 

If you have not received your order within 5 working days, please contact our Customer Services department.


1. You can email our Customer Service department via our contact form here
2. You can telephone on +44(0)1684 310099 
3. You can write to us at Cytoplan Ltd,Unit 98B, Blackpole Trading Estate West, Worcester, Worcestershire, WR3 8TJ

  • Provides folic acid as methylfolate (5-MTHF) for optimum absorption

  • Methylfolate is 7 x more bioeffective than folic acid and the safest form of folate 

  • Small easy to take capsules

  • Recommended folate (folic acid) level for pregnancy and preconception 

     

About our Methylfolate supplement 

Provides folic acid as methylfolate, 400ug per capsule. In a wholefood, stable and active form that is better used by your body than folic acid. Fulfils all the known uses of folic acid. 

Folate supplement benefits vs folic acid 

Many supplements contain folic acid; however folic acid must undergo several steps within the body to be converted to the active form – 5-MTHF. The final step in this conversion is carried out in your body by an enzyme called MTHFR and some people have genetic mutations which means this enzyme has reduced efficiency in converting folic acid to 5MTHF. 

Methylfolate does not need to be converted; it is in the active form, ready for use by the body. 

Functions of folic acid

Folic acid contributes to normal homocysteine metabolism. This is important as high homocysteine is a risk factor for several chronic diseases, including cardiovascular disease and cognitive decline.

Folate is used in the methylation cycle, something which occurs in all the cells of your body. Methylation is a chemical process that occurs a billions of times a second and is needed for the proper functioning of almost all body systems.  

Methylation functions: 

  • Detoxing environmental toxins 
  • Regulating hormones 
  • Energy production 
  • Production of neurotransmitters 
  • Production of immune cells 
  • Metabolism of homocysteine 
  • and many more! 

Methylation involves transferring molecules called ‘methyl groups’ to and from compounds to allow them to work optimally in the body. Methyl donors include folate, B12 and B6, among other nutrients, which are vital to normal methylation and therefore homocysteine metabolism.

Methyl folate (or 5-MTHF) is readily able to donate a methyl group to the amino acid homocysteine which is then converted to methionine, which is then used to form S-adenosylmethionine (SAM-e). SAM-e is used in many metabolic processes that require a methyl group. 

Folate contributes to normal: 

  • psychological function. 
  • blood formation. 
  • homocysteine metabolism. 
  • maternal tissue growth during pregnancy. 
  • immune system function. 
  • amino acid synthesis – can we give an example? 
  • contributes to the reduction of tiredness and fatigue. 
  • has a role in the process of cell division. 

What is the best folic acid for pregnancy? 

Supplementing with folic acid during preconception and pregnancy increases the mother’s folate status. Low levels in mum are a risk factor in the development of neural tube defects, such as spina bifida, in the developing foetus. 

You can find the government recommended daily dose of 400µg of folic acid in its optimally absorbed and naturally active form of methylfolate in our comprehensive pregnancy multivitamin and mineral, Pregna-Plan

Methylfolate - 1 capsule will provide on average:
Active Nutrient Strength %NRV*
Folic Acid as 5 methyltetrahydrofolate 400µg 200
+NRV = Nutritional Reference Value
* Indicates no NRV
Ingredients:

Folic acid (as 5 methyltetrahydrofolate), alfalfa (Medicago sativa) powder, brown rice flour, natural rice extract, Hydroxypropyl methylcellulose (capsule shell).

Suggested Intake:

One capsule daily with food as a food supplement or as directed by a practitioner.

Suitable for:

Vegetarians, vegans and for people with Candida and yeast sensitivities.

Contraindications:

None.

Non-Active Ingredients:

Maltodextrin, stearic acid, HPMC (vegetable cellulose, capsule shell).

Non GM & Free From:

GMO, wheat, gluten, soy, dairy, added sugar, colourings & flavourings.

Storage:

Keep cool, dry & out of direct sunlight.

For UK-delivered orders that are under £25.00, we charge a nominal postage and packing fee of £4.50. UK orders of £25.00 and over are DELIVERED FREE OF CHARGE. 

Dependent on weight, your order will either be sent by Royal Mail tracked service or via our nominated courier. A signature is required on receipt of the goods if delivered by our courier. 

Please check all requirements (import taxes, customs regulations etc) regarding deliveries to countries outside the UK. Cytoplan Ltd cannot be held responsible for parcels that do not comply with the import regulations of the destination country.

We cannot guarantee next day delivery, although you should receive your order within 2-3 working days. 

If you have not received your order within 5 working days, please contact our Customer Services department.


1. You can email our Customer Service department via our contact form here
2. You can telephone on +44(0)1684 310099 
3. You can write to us at Cytoplan Ltd,Unit 98B, Blackpole Trading Estate West, Worcester, Worcestershire, WR3 8TJ

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Methylfolate
Methylfolate
SKU: 3319/SB3319
£13.90 from
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